CREB3 Antibody - BSA Free

Western Blot: CREB3 Antibody [NBP1-32065] - Sample (30 ug of whole cell lysate) A: H1299 10% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: CREB3 Antibody [NBP1-32065] - Paraffin-embedded A549 xenograft, using antibody at 1:100 dilution.

• Reactivity: Hu, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CREB3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CREB3 Antibody - BSA Free (NBP1-32065) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CREB3. The exact sequence is proprietary.
• Localization: Endoplasmic reticulum membrane, Processed cyclic AMP-responsive element-binding protein 3: Nucleus
• Predicted Species: Rhesus Macaque (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CREB3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 44 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 40% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Protein A purified

Alternate Names for CREB3 Antibody - BSA Free

• basic leucine zipper protein
• cAMP responsive element binding protein 3 (luman)
• cAMP responsive element binding protein 3
• cAMP-responsive element-binding protein 3
• CREB-3
• cyclic AMP response element (CRE)-binding protein/activating transcriptionfactor 1
• cyclic AMP-responsive element-binding protein 3
• LUMAN
• LZIPMGC15333
• MGC19782
• Transcription factor LZIP-alpha

Background

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: CREB3