Corticotropin Releasing Factor Antibody (E1) - BSA Free

Western Blot: Corticotropin Releasing Factor Antibody (E1) [NBP3-41165] - Sample: Lane1: Human Placenta lysate; Lane2: Rat Cerebrum lysate; Lane3: Rat Pituitary lysate Primary Ab: 0.5ug/ml NBP3-41165; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

• Reactivity: Hu, Rt
• Applications: WB
• Clone: E1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.64 mg/ml

Corticotropin Releasing Factor Antibody (E1) - BSA Free Summary

• Description: Novus Biologicals Mouse Corticotropin Releasing Factor Antibody (E1) - BSA Free (NBP3-41165) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human Corticotropin Releasing Factor (Uniprot#: P06850; Ser154-Ile194 (Uniprot#: P06850)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CRH
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 0.64 mg/ml
• Purity: Protein A or G purified

Alternate Names for Corticotropin Releasing Factor Antibody (E1) - BSA Free

• corticoliberin
• corticotropin releasing hormone
• Corticotropin-releasing hormone
• CRFCorticotropin-releasing factor

Background

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH issecreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH hasbeen observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency hasmultiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to productionin the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed inthe placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturitionand delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, inaddition to its metabolic functions, CRH may act as a trigger for parturition. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CRH