Complement Component C2 Antibody (ARGX-117) - Humanized - Low Endotoxin, Azide and BSA Free

Immobilized human Complement C2 Protein at 2 ug/mL can bind Complement Component C2 Antibody (ARGX-117) - Humanized, EC50=0.004283 ug/mL.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: ARGX-117
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free
• Concentration: LYOPH

Complement Component C2 Antibody (ARGX-117) - Humanized - Low Endotoxin, Azide and BSA Free Summary

• Description: Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Complement C2
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: C2
• Purity: Protein A purified
• Endotoxin Note: < 0.001EU/ug,determined by LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Complement Component C2 Antibody (ARGX-117) - Humanized - Low Endotoxin, Azide and BSA Free

• C2
• C3/C5 convertase
• CO2
• complement C2
• complement component 2
• Complement Component C2
• DKFZp779M0311
• EC 3.4.21
• EC 3.4.21.43

Background

Complement C2 functions as part of the classical pathway complement system. Lack of complement C2 has been linked with some autoimmune diseases and recurrent/invasive infections. This protein is known to have interactions with C3, C4B, C5, PSMA4 and MASP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C2
• Uniprot:
  • P06681()