Complement Component C2 Antibody (ARGX-117) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: ARGX-117
• Clonality: Monoclonal
• Host: Human
• Conjugate: CoraFluor 1

Complement Component C2 Antibody (ARGX-117) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Complement C2
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: C2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Complement Component C2 Antibody (ARGX-117) [CoraFluor™ 1]

• C2
• C3/C5 convertase
• CO2
• complement C2
• complement component 2
• Complement Component C2
• DKFZp779M0311
• EC 3.4.21
• EC 3.4.21.43

Background

Complement C2 functions as part of the classical pathway complement system. Lack of complement C2 has been linked with some autoimmune diseases and recurrent/invasive infections. This protein is known to have interactions with C3, C4B, C5, PSMA4 and MASP1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C2