Complement Component C1s Antibody - Humanized, IgG4SP, (Research Grade sutimlimab Biosimilar) - Low Endotoxin, Azide and BSA Free

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Immobilized human C1S His at 2 ug/mL can bind Complement Component C1s Antibody (sutimlimab) - Humanized, IgG4SP, EC50=0.006163 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Format
Low Endotoxin, Azide and BSA Free
Concentration
LYOPH

Order Details

Complement Component C1s Antibody - Humanized, IgG4SP, (Research Grade sutimlimab Biosimilar) - Low Endotoxin, Azide and BSA Free Summary

Description
Expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'sutimlimab'.

IgG4SP is human IgG4 with S228P mutation.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
C1s
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
C1S
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Array

  • basic proline-rich peptide IB-1
  • C1 esterase
  • C1S
  • complement C1s subcomponent
  • Complement component 1 subcomponent s
  • complement component 1, s subcomponent
  • Complement Component C1s
  • EC 3.4.21
  • EC 3.4.21.42
  • FLJ44757

Background

C1s encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C1S
Uniprot