Complement C4c Antibody (99-72-18) - BSA Free

Immunohistochemistry: Complement C4c Antibody (99-72-18) - BSA Free [NBP3-12091] - IF staining of human kidney with NBP3-12091. Strong staining of veins of nephritis kidney. Dilution: 1:200

Immunohistochemistry: Complement C4c Antibody (99-72-18) - BSA Free [NBP3-12091] - IHC staining of human kidney with NBP3-12091. Strong staining of veins of nephritis kidney. Dilution: 1:600

Immunohistochemistry: Complement C4c Antibody (99-72-18) - BSA Free [NBP3-12091] - IHC staining of human liver with NBP3-12091. Cytoplasm of hepatocytes moderately labelled and plasma of veins strongly in liver tissue. Dilution: 1:600

Immunohistochemistry: Complement C4c Antibody (99-72-18) - BSA Free [NBP3-12091] - IHC staining in human tonsil with NBP3-12091. Plasma in lumen of veins is stained strongly as well as follicular dendritic cells in germinal center of tonsil. Dilution: 1:600

Immunohistochemistry: Complement C4c Antibody (99-72-18) - BSA Free [NBP3-12091] - IF staining in human tonsil with NBP3-12091. Plasma in lumen of veins is stained strongly in tonsil tissue. Dilution: 1:200

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC, IP
• Clone: 99-72-18
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Complement C4c Antibody (99-72-18) - BSA Free Summary

• Immunogen: Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR).
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: C4B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Complement C4c Antibody (99-72-18) - BSA Free

• basic C4
• Basic complement C4
• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
• C4B1
• C4B12
• C4B2
• C4B3
• C4FMGC164979
• CH
• Chido form of C4
• CO4C4B5
• complement C4-B
• complement C4B1a
• complement component 4B (Chido blood group)
• complement component 4B
• CPAMD3FLJ60561
• EC 2.1.1.144
• EC 2.7.11

Background

C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble). C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa). C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C4B