Collagen VI Native Protein

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Product Details

Summary
Reactivity BvSpecies Glossary
Applications WB, ELISA, IHC
Concentration
1.0 mg/ml

Order Details

Collagen VI Native Protein Summary

Description
Native COL6A1 protein.

Source: Bovine Placenta

Preparation
Method
This product has been prepared from Bovine Placenta and is chromatographically and immunologically pure. This product reacts with anti-Collagen Type VI. Reaction with Rockland's anti-Collagen I, II, III, IV or V is negligible (typically less than 1% cross reactivity was detected by ELISA).
Protein/Peptide Type
Native Protein
Gene
COL6A1
Purity
SDS-PAGE

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry 1:10 - 1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.5 M Sodium Acetate, pH 4.5
Preservative
0.01% Sodium Azide
Concentration
1.0 mg/ml
Purity
SDS-PAGE

Alternate Names for Collagen VI Native Protein

  • Collagen 6
  • collagen alpha-1(VI) chain
  • collagen VI, alpha-1 polypeptide
  • collagen, type VI, alpha 1
  • Collagen-6
  • human mRNA for collagen VI alpha-1 C-terminal globular domain10alpha 1 (VI) chain (61 AA)
  • OPLL

Background

In muscle tissue, collagen serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. A collagen may be defined as a protein containing sizable domain(s) of triple-helical conformation. Type IV collagen is a major macromolecular constituent of basement membranes and can be readily isolated from basement-membrane-rich tissues or highly vascularized tissues such as the placental villi. This collagen appears to be largely restricted to structures identifiable as basement membranes. In contrast, type VI collagen appears to be prevalent in several tissues even though it has been isolated largely from placental villi preparations. The extent to which type VII and VIII collagens are distributed is not known.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol COL6A1