Coagulation Factor XIV/Protein C Antibody [Alexa Fluor™ Plus 555]

• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor Plus 555

Coagulation Factor XIV/Protein C Antibody [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human Coagulation Factor XIV/Protein C in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Coagulation Factor XIV/Protein C Antibody [Alexa Fluor™ Plus 555]

• Anticoagulant protein C
• APC
• Autoprothrombin IIA
• Blood coagulation factor XIV
• Coagulation Factor XIV
• EC 3.4.21
• EC 3.4.21.69
• PC
• PROC
• PROC1
• protein C (inactivator of coagulation factors Va and VIIIa)
• Protein C
• vitamin K-dependent protein C

Background

Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1‑32), a propeptide (aa 33‑42), and a mature chain (aa 43‑461), which can be converted into two disulfide-linked chains (light: aa 43‑199 and heavy: aa 200‑461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.