CLN6 Antibody - BSA Free

Immunohistochemistry-Paraffin: CLN6 Antibody - BSA Free [NBP3-05809] - Immunochemical staining of human CLN6 in human stomach with NBP3-05809 at 1:100 dilution, formalin-fixed paraffin embedded sections.

Immunohistochemistry-Paraffin: CLN6 Antibody - BSA Free [NBP3-05809] - Immunochemical staining of human CLN6 in human kidney with NBP3-05809 at 1:100 dilution, formalin-fixed paraffin embedded sections.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CLN6 Antibody - BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with E. coli-derived Human CLN6 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLN6
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:50-1:200

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.03% Proclin 300
• Purity: Antigen and protein A Affinity-purified

Alternate Names for CLN6 Antibody - BSA Free

• ceroid-lipofuscinosis neuronal protein 6
• ceroid-lipofuscinosis, neuronal 6, late infantile, variant
• FLJ20561
• HsT18960
• nclf
• Protein CLN6

Background

CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLN6