Cited-2 Antibody

Product Discontinued

Cited-2 Antibody Summary

• Immunogen: Synthetic peptide with sequence DFVCKQQPSRVSC, representing the C Terminus of the human protein (residues 258-270) according to NP_006070.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CITED2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA 1:16000
• Application Notes: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: No signal obtained yet but low background observed in human testis, U937, 3T3, A431and 293 lysates at upto 1ug/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Reactivity Notes

Human, mouse and rat.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for Cited-2 Antibody

• Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain2,cbp/p300-interacting transactivator 2
• Cited2
• Cited-2
• MRG-1
• MRG1melanocyte-specific gene 1-related gene 1
• MSG1-related gene 1
• MSG-related protein 1
• P35srj

Background

Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a proposed negative regulator for hypoxia-inducible factor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptional response to hypoxia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CITED2
• Entrez:
  • 10370(Human)
  • 17684(Mouse)
  • 114490(Rat)
• Uniprot:
  • NP_006070.(Human)