CIP2A Antibody (2G10) [DyLight 650]


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Product Details

Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
DyLight 650

CIP2A Antibody (2G10) [DyLight 650] Summary

A synthetic peptide made to a C-terminal portion of the human CIP2A protein. [UniProt# Q8TCG1]
A 300 amino acid portion of the C-terminus.
p90 autoantigen (2G10)
IgG2b Kappa
Protein G purified
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  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This CIP2A antibody is useful for Immunocytochemistry/Immunofluorescence and Western Blot. In ICC/IF, strong cytoplasmic staining is observed in U20s cells. In Western Blot analysis, a band is seen at ~90 kDa representing CIP2A.

Reactivity Notes

Human, mouse, rat and primate. Other species have not been tested.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CIP2A Antibody (2G10) [DyLight 650]

  • Cancerous inhibitor of PP2A
  • CIP2A
  • FLJ12850
  • KIAA1524
  • MGC163436
  • p90 autoantigen
  • p90
  • protein CIP2A


Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB110-59722APC
Biotin Labeled NB110-59722B
DyLight 350 Labeled NB110-59722UV
DyLight 405 Labeled NB110-59722V
DyLight 488 Labeled NB110-59722G
DyLight 550 Labeled NB110-59722R
DyLight 680 Labeled NB110-59722FR
DyLight 755 Labeled NB110-59722IR
FITC Labeled NB110-59722F
HRP Labeled NB110-59722H
PE Labeled NB110-59722PE

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Bioinformatics Tool for CIP2A Antibody (NB110-59722C)

Discover related pathways, diseases and genes to CIP2A Antibody (NB110-59722C). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for CIP2A Antibody (NB110-59722C)

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Blogs on CIP2A.

CIP2A - A lean, mean, oncoprotein machine
The CIP2A protein was originally identified as p90, a cytoplasmic auto-antigen from the serum of a cancer patient. It was later found to inhibit protein phosphatase 2A (PP2A) activity as well as interact with c-myc. CIP2A's inhibitory activity blocks...  Read full blog post.

CIP2A: The Cancerous Inhibitor of Protein Phosphatase 2A
The autoantigen p90 is a recently discovered protein that binds to and inhibits Protein Phosphatase 2A (PP2A) activity, thereby playing a critical role in cancer progression. Thus, p90 was renamed the "cancerous inhibitory protein of PP2A" or CIP2A....  Read full blog post.

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Gene Symbol KIAA1524