cIAP-2/HIAP-1 Antibody [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

cIAP-2/HIAP-1 Antibody [HRP] Summary

Immunogen
Synthetic peptide made to an internal portion of human cIAP2 (within residues 100-200). [Swiss-Prot# Q13489]
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BIRC3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This cIAP2 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry paraffin embedded sections and Western blot analysis, where a band can be seen at ~64 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for cIAP-2/HIAP-1 Antibody [HRP]

  • AIP1
  • API2
  • BIRC3 baculoviral IAP repeat containing 3
  • BIRC3
  • cIAP2
  • c-IAP2
  • cIAP-2
  • HAIP1
  • HIAP1
  • HIAP-1
  • MALT2
  • MIHC
  • RNF49

Background

cIAP2 is an apoptotic suppressor. Apoptosis is activated by an array of stimuli including members of the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. These proteins contain a baculovirus IAP repeat (BIR) domain which interact with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form a heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). This complex may play a role in the inhibition of apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional cIAP-2/HIAP-1 Products

Bioinformatics Tool for cIAP-2/HIAP-1 Antibody (NBP1-27972H)

Discover related pathways, diseases and genes to cIAP-2/HIAP-1 Antibody (NBP1-27972H). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for cIAP-2/HIAP-1 Antibody (NBP1-27972H)

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Pathways for cIAP-2/HIAP-1 Antibody (NBP1-27972H)

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PTMs for cIAP-2/HIAP-1 Antibody (NBP1-27972H)

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Research Areas for cIAP-2/HIAP-1 Antibody (NBP1-27972H)

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Blogs on cIAP-2/HIAP-1.

cIAP2 - balancing cell death and cell survival
The inhibitor of apoptosis proteins (IAPs) are important regulators of cell death and inflammation. The cellular inhibitor of apoptosis protein 2 (cIAP2) contains three Baculovirus IAP repeat (BIR) domains, a Ubiquitin associated (UBA) domain, and...  Read full blog post.

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Bioinformatics

Gene Symbol BIRC3
Entrez