cIAP-2/HIAP-1 Antibody [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 680

cIAP-2/HIAP-1 Antibody [Alexa Fluor™ Plus 680] Summary

• Immunogen: Synthetic peptide made to an internal portion of human cIAP2 (within residues 100-200). [Swiss-Prot# Q13489]
• Localization: Cytoplasm
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BIRC3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for cIAP-2/HIAP-1 Antibody [Alexa Fluor™ Plus 680]

• AIP1
• API2
• BIRC3 baculoviral IAP repeat containing 3
• BIRC3
• cIAP2
• c-IAP2
• cIAP-2
• HAIP1
• HIAP1
• HIAP-1
• MALT2
• MIHC
• RNF49

Background

cIAP2 (baculoviral IAP repeat containing 3) belongs to the IAP family which are suppressors of apoptosis. cIAP2 has a variety of functions including regulation of caspases, modulating inflammatory immunity and signaling and cell proliferation. This protein is known to have interactions with TRAF2, DIABLO, RIPK1, RIPK2 and CASP3. cIAP2 has been studied in relation to lymphoma, leukemia, and several forms of cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BIRC3