CHD7 Recombinant Enzymes

• Reactivity: Hu
• Applications: NULL

CHD7 Recombinant Enzymes Summary

• Description: Human CHD7 (aa 2-2996) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q9P2D1-1)
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Enzymes
• Gene: CHD7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • N/A

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for CHD7 Recombinant Enzymes

• ATP-dependent helicase CHD7
• CHD7
• CHD-7
• chromodomain helicase DNA binding protein 7 isoform CRA_e
• chromodomain helicase DNA binding protein 7
• chromodomain-helicase-DNA-binding protein 7
• EC 3.6.1
• EC 3.6.4.12
• FLJ20357
• FLJ20361
• IS3
• KIAA1416KAL5

Background

Human CHD7 is a chromodomain helicase DNA-binding protein and mutations in the CHD7 gene are a major cause of CHARGE syndrome. CHARGE syndrome is a well characterized multiple-malformation syndrome with distinctive diagnostic critera. Anomalies include ocular coloboma, choanal atresia, cranial nerve defects, distinctive external and inner ear abnormalities, hearing loss, cardiovascular malformations, urogenital anomalies, and growth retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CHD7