Cdc14B Antibody

Immunohistochemistry-Paraffin: Cdc14B Antibody [NBP2-98128] - Staining of human Cdc14B in human placenta with rabbit polyclonal antibody at 1:500 dilution.

Immunohistochemistry-Paraffin: Cdc14B Antibody [NBP2-98128] - Staining of human Cdc14B in human esophagus with rabbit polyclonal antibody at 1:500 dilution.

Product Discontinued

Cdc14B Antibody Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with E. coli-derived Human Cdc14B fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDC14B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200-1:1000
  • Immunohistochemistry-Paraffin 1:200-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.0)
• Preservative: 0.03% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for Cdc14B Antibody

• CDC14 cell division cycle 14 homolog B (S. cerevisiae)
• CDC14 cell division cycle 14 homolog B
• S. cerevisiae) homolog B

Background

Cdc14B is encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC14B