CD94 Antibody (131412) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: Flow, B/N, CyTOF-ready
• Clone: 131412
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

CD94 Antibody (131412) [mFluor Violet 610 SE] Summary

• Immunogen: BaF3 mouse pro-B cell line transfected with human CD94 and NKG2A
• Specificity: Recognizes human CD94 both in its homodimeric form and as a heterodimer with either NKG2A or NKG2C.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KLRD1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD94 Antibody (131412) [mFluor Violet 610 SE]

• CD94 antigen
• CD94
• CD94natural killer cells antigen CD94
• Killer cell lectin-like receptor subfamily D member 1
• killer cell lectin-like receptor subfamily D, member 1
• KLRD1
• KP43
• NK cell receptor

Background

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. KLRD1 has two alternatively spliced variants that differ in the presence or absence of exon 2 sequence.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRD1