NKG2C/CD159c/KLRC2 Antibody (134591) [Unconjugated] Summary
BaF3 mouse pro-B cell line transfected with human NKG2C/CD159c and CD94
Detects human NKG2C/CD159c heterodimer with CD94 in flow cytometry. It does not cross-react with the human NKG2A/CD94 heterodimer or with the human CD94 homodimer.
Details of Functionality
ActivityAssaywCitation not found None
Test in a species/application not listed above to receive a full credit towards a future purchase.
Flow Cytometry 2.5 ug/10^6 cells CyTOF-reported
Publications using MAB138 in the following applications:
Packaging, Storage & Formulations
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for NKG2C/CD159c/KLRC2 Antibody (134591) [Unconjugated]
CD159 antigen-like family member C CD159c antigen CD159c killer cell lectin-like receptor subfamily C, member 2 KLRC2 MGC138244 NK cell receptor C NKG2-C type II integral membrane protein NKG2C NKG2-C NKG2CNKG2-C-activating NK receptor Background
NKG2C, also known as hemoglobin scavenger receptor, is a type II transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
for 1 year from date of receipt.
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Applications: WB, CyTOF-ready, ICFlow
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Applications: WB, ELISA
Applications: Flow, AgAct, CyTOF-reported
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Publications for NKG2C/CD159c/KLRC2 Antibody (MAB138)(12)
We have publications tested in 1 confirmed species: Human.
We have publications tested in 1 application: Flow.
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Show All 12 Publications.
Publications using MAB138
G Martrus, T Kautz, S Lunemann, L Richert, L Glau, W Salzberger, H Goebels, A Langenecke, L Hess, T Poch, C Schramm, KJ Oldhafer, M Koch, E Tolosa, B Nashan, M Altfeld Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells PLoS ONE, 2017;12(8):e0182532. 2017 [PMID: 28792982] (Flow,, Human) Flow
Raphaëlle Riou Severe symptomatic primary HCMV infection despite effective innate and adaptive immune responses J. Virol, 2016;0(0):. 2016 [PMID: 28031361] (Flow,, Human) Flow
Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol, 2015;194(6):2467-71. 2015 [PMID: 25672754] (Flow,, Human) Flow
Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le V, Galun E, Horejsi V, Isakov O, Shomron N, Wolf D, Hengel H, Mandelboim O MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog, 2014;10(2):e1003963. 2014 [PMID: 24586166] (Flow,, Human) Flow
Saghafian-Hedengren S, Sohlberg E, Theorell J, Carvalho-Queiroz C, Nagy N, Persson J, Nilsson C, Bryceson Y, Sverremark-Ekstrom E Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells. J Virol, 2013;87(24):13446-55. 2013 [PMID: 24089567] (Flow,, Human) Flow
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2013;43(2):480-7. 2013 [PMID: 23161492] (Flow,, Human) Flow
Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 2012;8(1):e1002486. 2012 [PMID: 22253598] (Flow,, Human) Flow
Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L NKG2A inhibits NKG2C effector functions of gammadelta T cells: implications in health and disease. J. Leukoc. Biol., 2011;89(1):75-84. 2011 [PMID: 20952657] (Flow,, Human) Flow
Yu J, Mao HC, Wei M, Hughes T, Zhang J, Park IK, Liu S, McClory S, Marcucci G, Trotta R, Caligiuri MA CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood, 2010;115(2):274-81. 2010 [PMID: 19897577] (Flow,, Human) Flow
Beziat V, Nguyen S, Lapusan S, Hervier B, Dhedin N, Bories D, Uzunov M, Boudifa A, Trebeden-Negre H, Norol F, Marjanovic Z, Marie JP, Vernant JP, Debre P, Rio B, Vieillard V Fully functional NK cells after unrelated cord blood transplantation. Leukemia, 2009;23(4):721-8. 2009 [PMID: 19151772] (Flow,, Human) Flow
Show All 12 Publications.
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