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HAF016). A specific band was detected for CD94 at approximately 75 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8." class="big_lightbox" target="_blank">
Species: Hu, Mu, Ca Applications: WB Host: Sheep Polyclonal
MAB0041) followed by anti-Mouse IgG Allophycocyanin-conjugated secondary antibody (F0101B) and Mouse Anti-Human CD56 Phycoerythrin-conjugated Monoclonal Antibody (FAB24086P). Staining was performed using our Staining Membrane-associated Proteins protocol." class="big_lightbox" target="_blank">
Species: Hu Applications: Flow Host: Mouse Monoclonal
9759-NK) is immobilized at 2 µg/mL (100 µL/well), Recombinant Human CD94 Fc Chimera (Catalog # 10281-CD) binds with an ED50 of 1.25-10 µg/mL." class="big_lightbox" target="_blank">
9198-NK) is coated at 0.5 µg/mL, Recombinant Human CD94 (Catalog # 9270-CD) binds with an ED50 of 0.1-0.6 µg/mL." class="big_lightbox" target="_blank">
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. KLRD1 has two alternatively spliced variants that differ in the presence or absence of exon 2 sequence.