CD83 Antibody (DMC436) - Chimeric

• Reactivity: Hu
• Applications: Flow
• Clone: DMC436
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Concentration: LYOPH

CD83 Antibody (DMC436) - Chimeric Summary

• Description: This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: CD83 recombinant protein expressed in mammalian cells (Accession# Q01151). The exact amino acid sequence is proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: CD83
• Purity: Antigen Affinity-purified from cell culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:100

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: PBS, pH 7.4, 5-8% Trehalose
• Preservative: Trehalose
• Concentration: LYOPH
• Purity: Antigen Affinity-purified from cell culture supernatant
• Reconstitution Instructions: Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Alternate Names for CD83 Antibody (DMC436) - Chimeric

• B-cell activation protein
• BL11
• BL11CD83 antigen
• CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
• CD83 molecule
• CD83
• Cell surface protein HB15
• cell-surface glycoprotein
• HB15
• HB15hCD83

Background

CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD83