CD8 beta Antibody (H35-17.2) [FITC]

Flow Cytometry: CD8 beta Antibody (H35-17.2) [FITC] [NBP1-44038] - Staining of BALB/c splenocytes with Anti-Mouse CD8a APC and 0.125 ug of Rat IgG2b k Isotype Control FITC (left) or 0.125 ug of Anti-Mouse CD8b FITC (right). Cells in the lymphocyte gate were used for analysis

• Reactivity: Mu
• Applications: Flow
• Clone: H35-17.2
• Clonality: Monoclonal
• Host: Rat
• Conjugate: FITC

CD8 beta Antibody (H35-17.2) [FITC] Summary

• Immunogen: The immunogen for this antibody was CD8.
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: CD8B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
• Application Notes: This H35-17.2 antibody has been tested by flow cytometric analysis of mouse splenocytes and thymocytes.

Reactivity Notes

This antibody is reactive to Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS (pH 7.2) with 0.1% gelatin
• Preservative: 0.09% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for CD8 beta Antibody (H35-17.2) [FITC]

• CD8 antigen, beta polypeptide 1 (p37)
• CD8 beta
• CD8b antigen
• CD8b molecule
• CD8b
• CD8B1
• CD8B1P37
• Leu2
• LY3
• LYT3
• MGC119115
• P37
• T lymphocyte surface glycoprotein beta chain
• T-cell surface glycoprotein CD8 beta chain

Background

The H35-17.2 monoclonal antibody reacts with the mouse CD8beta molecule. The CD8beta chain associates with the CD8alpha chain to form the CD8alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. CD8 binds to MHC class I and plays a role in T cell development and activation of mature T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD8B
• Entrez:
  • 12526(Mouse)
• Uniprot:
  • P10300(Mouse)