CD68/SR-D1 Antibody [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 700

CD68/SR-D1 Antibody [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CD68/SR‑D1
  Asn22-Ile320
  Accession # AAB25811
• Specificity: Detects human CD68/SR‑D1 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD68/SR-D1 Antibody [Alexa Fluor® 700]

• CD_antigen: CD68
• CD68 antigen
• CD68 molecule
• CD68
• DKFZp686M18236
• gp110
• LAMP4
• macrophage antigen CD68
• Macrosialin
• SCARD1
• scavenger receptor class D, member 1
• SRD1
• SR-D1

Background

CD68, also called Scavenger Receptor D1 (SR-D1) or macrosialin in mouse, is a 110 kDa type I transmembrane glycoprotein that belongs to the LAMP family of molecules (1). It contains a 300 amino acid (aa) extracellular region that is rich in threonine and serine, a likely attachment site for multiple carbohydrates. Human CD68 shares 74% aa sequence identity to mouse CD68 in the extracellular region. CD68 is found on monocytes and macrophages and serves as a scavenger receptor for oxidized LDL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.