CD68/SR-D1 Antibody (C68/684) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, Fe, Pm, Rt(-)Species Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
C68/684
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

CD68/SR-D1 Antibody (C68/684) [Janelia Fluor® 549] Summary

Immunogen
Subcellular fraction of human alveolar macrophages
Localization
Cytoplasmic
Marker
Macrophage Marker
Specificity
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD68
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD68/SR-D1 Antibody (C68/684) [Janelia Fluor® 549]

  • CD68 antigenmacrophage antigen CD68
  • CD68 molecule
  • CD68
  • DKFZp686M18236
  • gp110
  • Macrosialin
  • SCARD1
  • scavenger receptor class D, member 1
  • SRD1
  • SR-D1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for CD68/SR-D1 Antibody (NBP2-34587JF549) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34587AF350
Alexa Fluor 405 NBP2-34587AF405
Alexa Fluor 488 NBP2-34587AF488
Alexa Fluor 532 NBP2-34587AF532
Alexa Fluor 594 NBP2-34587AF594
Alexa Fluor 647 NBP2-34587AF647
Alexa Fluor 700 NBP2-34587AF700
Alexa Fluor 750 NBP2-34587AF750
Allophycocyanin NBP2-34587APC
Allophycocyanin/Cy7 NBP2-34587APCCY7
Biotin NBP2-34587B
DyLight 350 NBP2-34587UV
DyLight 405 NBP2-34587V
DyLight 488 NBP2-34587G
DyLight 550 NBP2-34587R
DyLight 594 NBP2-34587DL594
DyLight 650 NBP2-34587C
DyLight 680 NBP2-34587FR
DyLight 755 NBP2-34587IR
FITC NBP2-34587F
HRP NBP2-34587H
Janelia Fluor 549 NBP2-34587JF549
Janelia Fluor 646 NBP2-34587JF646
PE NBP2-34587PE
PE/Atto594 NBP2-34587PEATT594
PE/Cy5.5 NBP2-34587PECY55
PE/Cy7 NBP2-34587PECY7
PerCP NBP2-34587PCP

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Blogs on CD68/SR-D1.

CD68 (Cluster of differentiation 68, GP110, LAMP4, SCARD1)
CD68 belongs to a growing family of hematopoietic mucin-like molecules known as lysosomal/endosomal-associated membrane glycoproteins (LAMPs). Other LAMP family members included leukosialin, stem cell antigen CD34, and GlyCAM-1. CD68 encodes a 110-kD...  Read full blog post.

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Bioinformatics

Gene Symbol CD68
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