CD55/DAF Antibody (MEM-118)


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Product Details

Reactivity Hu, PmSpecies Glossary
Applications Flow, IHC, IHC-P, IP
1.0 mg/ml

CD55/DAF Antibody (MEM-118) Summary

HPB-ALL human T cell line
The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells. HLDA V; WS Code AS S016
Size Exclusion Chromatography
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris Buffered Saline (TBS), approx. pH 8.0
15mM Sodium Azide
1.0 mg/ml
Size Exclusion Chromatography


  • Flow Cytometry 10 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Immunoprecipitation 1:50

Alternate Names for CD55/DAF Antibody (MEM-118)

  • CD55 antigen
  • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
  • CD55
  • CR
  • CRdecay accelerating factor for complement (CD55, Cromer blood group system)
  • CROMDAFcomplement decay-accelerating factor
  • DAF
  • decay accelerating factor for complement
  • TC


Avoidance by host tissues of attack by autologous complement proteins is dependent in part on the activities of membrane regulatory factors. One molecule involved in this control is a 70 kD glycoprotein termed decay-accelerating factor (DAF), or CD55. Interruption by CD55 of the complement sequence at an early step in activation effectively halts progression of the cascade and prevents consequent cell injury. In man, CD55 is expressed on the plasma membrane of all cell types that are in intimate contact with plasma complement proteins. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. CD55 also acts as the receptor for echovirus 7 and related viruses(echoviruses 13, 21, 29 and 33). It is attached to the membrane by a GPI-anchor.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB500-395AF405
Alexa Fluor (R) 488 Labeled NB500-395AF488
Alexa Fluor (R) 647 Labeled NB500-395AF647
Alexa Fluor (R) 700 Labeled NB500-395AF700
Allophycocyanin Labeled NB500-395APC
DyLight 350 Labeled NB500-395UV
DyLight 405 Labeled NB500-395V
DyLight 405LS Labeled NB500-395V3
DyLight 488 Labeled NB500-395G
DyLight 680 Labeled NB500-395FR
DyLight 755 Labeled NB500-395IR
PE Labeled NB500-395PE
PerCP Labeled NB500-395PCP

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Contact Information

Product PDFs


Gene Symbol CD55

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