CD5 Antibody (C5/473 + CD5/54/F6) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
C5/473 + CD5/54/F6
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

CD5 Antibody (C5/473 + CD5/54/F6) [Janelia Fluor® 646] Summary

Immunogen
Human CD5 recombinant protein (C5/473); A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6)
Localization
Cell surface
Marker
Mantle Cell Lymphoma Marker
Specificity
Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CD5
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD5 Antibody (C5/473 + CD5/54/F6) [Janelia Fluor® 646]

  • CD5 antigen (p56-62)
  • CD5 antigen
  • CD5 molecule
  • CD5
  • LEU1T-cell surface glycoprotein CD5
  • Lymphocyte antigen T1/Leu-1
  • T1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for CD5 Antibody (NBP2-34583JF646) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34583AF350
Alexa Fluor 405 NBP2-34583AF405
Alexa Fluor 488 NBP2-34583AF488
Alexa Fluor 532 NBP2-34583AF532
Alexa Fluor 594 NBP2-34583AF594
Alexa Fluor 647 NBP2-34583AF647
Alexa Fluor 700 NBP2-34583AF700
Alexa Fluor 750 NBP2-34583AF750
Allophycocyanin NBP2-34583APC
Allophycocyanin/Cy7 NBP2-34583APCCY7
Biotin NBP2-34583B
DyLight 350 NBP2-34583UV
DyLight 405 NBP2-34583V
DyLight 488 NBP2-34583G
DyLight 550 NBP2-34583R
DyLight 594 NBP2-34583DL594
DyLight 650 NBP2-34583C
DyLight 680 NBP2-34583FR
DyLight 755 NBP2-34583IR
FITC NBP2-34583F
HRP NBP2-34583H
Janelia Fluor 549 NBP2-34583JF549
Janelia Fluor 646 NBP2-34583JF646
PE NBP2-34583PE
PE/Atto594 NBP2-34583PEATT594
PE/Cy5.5 NBP2-34583PECY55
PE/Cy7 NBP2-34583PECY7

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