Recombinant Human CD48/SLAMF2 Protein

Product Discontinued

Recombinant Human CD48/SLAMF2 Protein Summary

• Description: A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 27-220 of Human CD48/SLAMF2
  
  

  Source:Baculovirus

  Amino Acid Sequence: ADPQGHLVHM TVVSGSNVTL NISESLPENY KQLTWFYTFD QKIVEWDSRK SKYFESKFKG RVRLDPQSGA LYISKVQKED NSTYIMRVLK KTGNEQEWKI KLQVLDPVPK PVIKIEKIED MDDNCYLKLS CVIPGESVNY TWYGDKRPFP KELQNSVLET TLMPHNYSRC YTCQVSNSVS SKNGTVCLSP PCTLARSHHH HHH

• Source: Baculovirus
• Protein/Peptide Type: Recombinant Protein
• Gene: CD48
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1.0 EU per 1ug of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 23.4 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human CD48/SLAMF2 Protein

• BCM1 surface antigen
• BCM1
• BCM1Leukocyte antigen MEM-102
• BLAST
• BLAST1
• BLAST1TCT.1
• B-lymphocyte activation marker BLAST-1
• CD48 antigen (B-cell membrane protein)
• CD48 antigen
• CD48 molecule
• CD48
• hCD48
• mCD48
• MEM-102
• SLAMF2

Background

CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CD48