CD45RC Antibody (C455.1F) [FITC]

Flow Cytometry: CD45RC Antibody (C455.1F) [FITC] [NBP1-28133] - Analysis of BALB/c splenocytes by multiple stainnig.

• Reactivity: Mu
• Applications: Flow
• Clone: C455.1F
• Clonality: Monoclonal
• Host: Rat
• Conjugate: FITC

CD45RC Antibody (C455.1F) [FITC] Summary

• Immunogen: An exon C-dependent epitope of CD45 glycoprotein
• Specificity: An exon C-dependent epitope of CD45 glycoprotein
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: PTPRC
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for CD45RC Antibody (C455.1F) [FITC]

• B220
• CD45 antigen
• CD45R
• EC 3.1.3.48
• L-CA
• LY5
• protein tyrosine phosphatase, receptor type, C
• receptor-type tyrosine-protein phosphatase C
• T200 glycoprotein
• T200 leukocyte common antigen
• T200receptor type, c polypeptide

Background

The CD45 family of cell-surface glycoprotein antigens exist as a set of isoforms. (1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T-200 species. (1-4) The 'restricted' subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRC