CD45RC Products

Description

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Bioinformatics

Product By Gene ID	5788
Alternate Names	B220 CD45 antigen CD45R EC 3.1.3.48 L-CA LY5 protein tyrosine phosphatase, receptor type, C receptor-type tyrosine-protein phosphatase C T200 glycoprotein T200 leukocyte common antigen T200receptor type, c polypeptide

Research Areas for CD45RC

Find related products by research area and learn more about each of the different research areas below.

Hematopoietic Stem Cell Markers
Immunology
Mesenchymal Stem Cell Markers
Stem Cell Markers