CD43/Sialophorin Antibody (W3/13) [HRP]

• Reactivity: Rt
• Applications: WB, Flow, IHC
• Clone: W3/13
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

CD43/Sialophorin Antibody (W3/13) [HRP] Summary

• Immunogen: Rat thymocyte membrane glycoproteins
• Localization: Type I membrane protein.
• Specificity: Rat CD43 cell surface antigen.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SPN
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reacts with Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for CD43/Sialophorin Antibody (W3/13) [HRP]

• CD43 antigen
• CD43
• CD43)
• Galactoglycoprotein
• GALGP
• GPL115
• Leukocyte sialoglycoprotein
• Leukosialin
• LSN
• Ly-48
• sialophorin (gpL115, leukosialin, CD43)
• Sialophorin
• SPN

Background

CD43 is a key glycoprotein of thymocytes and T lymphocytes, which affects the physicochemical properties of the T-cell surface and plays a role in lectin binding. This antibody contains an extended rodlike structure that may protrude above the glycocalyx of the cell, allowing accessibility of multiple glycan chains for binding. During T-cell activation CD43 is actively removed from the T-cell-antigen-presenting cell contact site, thus suggesting CD43's role in negative regulation of the adaptive immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPN