CD40/TNFRSF5 Antibody (HB14)

Images

 
Immunohistochemistry-Paraffin: CD40/TNFRSF5 Antibody (HB14) [NBP1-39881] - Analysis of anti-CD40 antibody with human tonsil at concentration 10 ug/ml.
Flow Cytometry: CD40/TNFRSF5 Antibody (HB14) [NBP1-39881] - Analysis using the FITC conjugate of NBP1-39881. Staining of Human peripheral blood lymphocytes with HB14 FITC.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications Flow, IHC-P
Clone
HB14
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

CD40/TNFRSF5 Antibody (HB14) Summary

Immunogen
Human B cell line.
Specificity
Recognizes human CD40.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD40
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.5 ug/million cells
  • Immunohistochemistry-Paraffin 10 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CD40/TNFRSF5 Antibody (HB14)

  • B cell surface antigen CD40
  • B-cell surface antigen CD40
  • Bp50B cell-associated molecule
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • CD40 type II isoform
  • CD40
  • CD40L receptor
  • CDw40
  • MGC9013
  • nerve growth factor receptor-related B-lymphocyte activation molecule
  • p50
  • TNFRSF5
  • TNFRSF5CD40 antigen (TNF receptor superfamily member 5)
  • tumor necrosis factor receptor superfamily member 5
  • tumor necrosis factor receptor superfamily, member 5

Background

CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
NBP2-25208
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
MAB140
Species: Hu
Applications: Flow, IHC, CyTOF-ready, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NBP1-91499
Species: Mu, Bv
Applications: WB, ICC/IF, IHC
NB600-225
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
NBP2-02665
Species: Hu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP1-92684
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
796-IC
Species: Mu
NBP1-39881
Species: Hu, Pm
Applications: Flow, IHC-P

Publications for CD40/TNFRSF5 Antibody (NBP1-39881) (0)

There are no publications for CD40/TNFRSF5 Antibody (NBP1-39881).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CD40/TNFRSF5 Antibody (NBP1-39881) (0)

There are no reviews for CD40/TNFRSF5 Antibody (NBP1-39881). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CD40/TNFRSF5 Antibody (NBP1-39881). (Showing 1 - 2 of 2 FAQ).

  1. I wanna know does CD40 antibody for IHC-P comes with positive control slide?
    • Our CD40 antibodies do not come with positive control slides however you can use any type of primary carcinoma cell as a positive control. I recommend breast carcinoma as this is what we have tested our CD40 antibodies on.
  2. We are studying CD40L in our system. It has been known that both CD40 and CD11b are receptors for CD40L. We need CD40 antibody to neutralize CD40 binding to CD40L, then we may prove what is function for CD11b binding to CD40L. Do you have any CD40 Ab which has block function only between CD40 and CD40L, but not between CD11b and CD40L?
    • Unfortunately, none of our CD40 antibodies have been specifically tested for this application.

Secondary Antibodies

 

Isotype Controls

Additional CD40/TNFRSF5 Products

Bioinformatics Tool for CD40/TNFRSF5 Antibody (NBP1-39881)

Discover related pathways, diseases and genes to CD40/TNFRSF5 Antibody (NBP1-39881). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CD40/TNFRSF5 Antibody (NBP1-39881)

Discover more about diseases related to CD40/TNFRSF5 Antibody (NBP1-39881).
 

Pathways for CD40/TNFRSF5 Antibody (NBP1-39881)

View related products by pathway.

PTMs for CD40/TNFRSF5 Antibody (NBP1-39881)

Learn more about PTMs related to CD40/TNFRSF5 Antibody (NBP1-39881).
 

Research Areas for CD40/TNFRSF5 Antibody (NBP1-39881)

Find related products by research area.

Blogs on CD40/TNFRSF5

There are no specific blogs for CD40/TNFRSF5, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CD40/TNFRSF5 Antibody (HB14) and receive a gift card or discount.

Bioinformatics

Gene Symbol CD40
Entrez