CD300e/LMIR6 Antibody (UP-H2) [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB, Flow, Func, IP
• Clone: UP-H2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 700

CD300e/LMIR6 Antibody (UP-H2) [Alexa Fluor® 700] Summary

• Immunogen: CD300e-HA-transfected cells
• Specificity: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD300E
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Functional
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD300e/LMIR6 Antibody (UP-H2) [Alexa Fluor® 700]

• CD300 antigen like family member E
• CD300 antigen-like family member E
• CD300e antigenPIgR-2
• CD300e molecule
• CD300e
• CD300LE
• CD300LEPIgR2
• CLM2
• CLM-2
• CLM2CMRF35-A5
• CMRF35A5
• CMRF35-like molecule 2
• Immune receptor expressed on myeloid cells 2
• IREM-2
• IREM2IREM-2
• LMIR6
• Poly-Ig receptor 2
• Polymeric immunoglobulin receptor 2

Background

CD300LE is an activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells. It mediates activating signals by interacting with DAP12 (TYROBP; MIM 604142) (Aguilar et al., 2004 [PubMed 15557162]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD300E