Cytohesin 2 Antibody (6H5)

Images

 
Western Blot: Cytohesin 2 Antibody (6H5) [H00009266-M02] - CYTH2 monoclonal antibody (M02), clone 6H5 Analysis of CYTH2 expression in PC-12.
Immunocytochemistry/ Immunofluorescence: Cytohesin 2 Antibody (6H5) [H00009266-M02] - Analysis of monoclonal antibody to CYTH2 on HeLa cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: Cytohesin 2 Antibody (6H5) [H00009266-M02] - Analysis of monoclonal antibody to CYTH2 on formalin-fixed paraffin-embedded human colon. Antibody concentration 3 ug/ml.
Western Blot: Cytohesin 2 Antibody (6H5) [H00009266-M02] - Analysis of CYTH2 expression in transfected 293T cell line by CYTH2 monoclonal antibody (M02), clone 6H5.Lane 1: CYTH2 transfected lysate(46.5 KDa).Lane 2: ...read more
Sandwich ELISA: Cytohesin 2 Antibody (6H5) [H00009266-M02] - Detection limit for recombinant GST tagged CYTH2 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clone
6H5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Cytohesin 2 Antibody (6H5) Summary

Immunogen
PSCD2 (NP_059431, 314 a.a. ~ 399 a.a) partial recombinant protein with GST tag.VDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQE
Specificity
PSCD2 - pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CYTH2
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.
Publications
Read Publication using H00009266-M02.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytohesin 2 Antibody (6H5)

  • ARF exchange factor
  • ARF nucleotide-binding site opener
  • ARNOPH, SEC7 and coiled-coil domain-containing protein 2
  • CTS18.1
  • cytohesin 2
  • pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)
  • Protein ARNO
  • PSCD2LCTS18
  • PSCD2pleckstrin homology, Sec7 and coiled-coil domains 2
  • Sec7 and coiled/coil domains 2 (cytohesin-2)

Background

Pleckstrin homology, Sec7 and coiled/coil domains 2 (PSCD2) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. PSCD2 exhibits GEP activity in vitro with ARF1, ARF3, and ARF6. PSCD2 protein is 83% homologous to PSCD1. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cytohesin 2 Antibody (H00009266-M02)(1)

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WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol CYTH2
Entrez
OMIM
Uniprot