CD1c/BDCA-1 Antibody (M241) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: Func, IHC, IP
• Clone: M241
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

CD1c/BDCA-1 Antibody (M241) [Alexa Fluor™ Plus 594] Summary

• Additional Information: Clone M241 was used by HLDA to establish CD designation.
• Immunogen: MOLT 4 cell line
• Localization: Cell Membrane
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD1C
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Radioimmunoassay
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD1c/BDCA-1 Antibody (M241) [Alexa Fluor™ Plus 594]

• BDCA1
• BDCA-1
• c polypeptide
• CD1
• CD1A
• CD1c antigen
• CD1c molecule
• CD1c
• cortical thymocyte antigen CD1C
• differentiation antigen CD1-alpha-3
• R7
• T-cell surface glycoprotein CD1c

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD1C