CD1b Antibody (SN13)

Product Discontinued

CD1b Antibody (SN13) Summary

• Immunogen: The immunogen for this antibody was CD1b.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD1B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
• Application Notes: This SN13 antibody has been tested by flow cytometric analysis of SN13 cells. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 5 mg/ml
• Purity: Protein A or G purified

Alternate Names for CD1b Antibody (SN13)

• CD1
• CD1A
• CD1b antigen
• CD1B antigen, b polypeptide
• CD1b molecule
• CD1b
• cortical thymocyte antigen CD1B
• differentiation antigen CD1-alpha-3
• MGC125990
• MGC125991
• R1
• T-cell surface glycoprotein CD1b

Background

The SN13 monoclonal antibody reacts with human CD1b. The CD1 molecules are similar to MHC class I, but rather than presenting peptide antigens to T-cell receptors (TCR), they present a diversity of lipid and glycolipid antigens which are derived from self as well as from mycobacteria which include sphingolipids, mycolic acid derivatives and phosphatidylinositols such as liparabinomannan (LAM) and glucose monomycolate (GMM). CD1b is 45 kDa, and like the other CD1 antigens, is expressed as a heterodimer composed of the CD1b noncovalently paired with beta2-microglobulin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD1B