| Reactivity | HuSpecies Glossary |
| Applications | Flow, ICC/IF |
| Clone | 100-1A5 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Concentration | 0.2 mg/ml |
| Immunogen | Stimulated human leukocytes |
| Localization | Cell surface |
| Specificity | The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. |
| Isotype | IgM Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | CD1B |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Hu-chromosome location: 1q23.1 Functional Studies Order Ab without BSA & Azide. |
| Theoretical MW | 44 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Storage | Store at 4C. |
| Buffer | 10 mM PBS with 0.05% BSA |
| Preservative | 0.05% Sodium Azide |
| Concentration | 0.2 mg/ml |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Diseases for CD1b Antibody (NBP2-45243)Discover more about diseases related to CD1b Antibody (NBP2-45243).
| Pathways for CD1b Antibody (NBP2-45243)View related products by pathway.
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Research Areas for CD1b Antibody (NBP2-45243)Find related products by research area.
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![Immunocytochemistry/Immunofluorescence: RRM2 Antibody [NBP1-31661] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RRM2 protein stained by RRM2 antibody [N1C1] diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.](http://images.novusbio.com/fullsize2/RRM2-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-31661-img0011.jpg)
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![Immunohistochemistry-Paraffin: HLA DQA1 Antibody (JU17-34) [NBP2-75525] - Analysis of paraffin-embedded rat lung tissue using anti-HLA-DQA1 antibody. Counter stained with hematoxylin.](http://images.novusbio.com/fullsize2/HLA-DQA1-Antibody-(JU17-34)-Immunohistochemistry-Paraffin-NBP2-75525-img0003.jpg)
![Immunohistochemistry-Paraffin: HLA DQA1 Antibody (JU17-34) [NBP2-75525] - Analysis of paraffin-embedded human tonsil tissue using anti-HLA-DQA1 antibody. Counter stained with hematoxylin.](http://images.novusbio.com/fullsize2/HLA-DQA1-Antibody-(JU17-34)-Immunohistochemistry-Paraffin-NBP2-75525-img0001.jpg)
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![Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review.](http://images.novusbio.com/fullsize2/NOD2-Antibody-(2D9)-Immunohistochemistry-Frozen-NB100-524-img0016.jpg)
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![Immunohistochemistry-Paraffin: CD4 Antibody [NBP1-19371] - Alcohol-fixed paraffin-embedded rat spleen tissue. Dilution 1:150. Image from verified customer review.](http://images.novusbio.com/fullsize2/CD4-Antibody-Immunohistochemistry-Paraffin-NBP1-19371-img0014.jpg)
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