CD164 Antibody

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

CD164 Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CD164
  Gln24-Thr160
  Accession # Q9R0L9
• Specificity: Detects mouse CD164 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human CD164 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CD164
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD164 Antibody

• CD164 antigen
• CD164 molecule, sialomucin
• CD164
• Endolyn
• MGC-24
• MGC-24v
• MUC-24
• Multi-glycosylated core protein 24
• sialomucin

Background

CD164, also known as MGC-24 (Multi-glycosylated protein 24), is a type I transmembrane sialomucin containing two extracellular mucin domains linked by a non‑mucin domain. Depending on the cell type, CD164 has been localized to endosomes and lysosomes or the plasma membrane. When present at the cell surface, CD164 has been shown to function as an adhesion molecule that may play a role in hematopoiesis. At least two mouse CD164 splice variants have been reported. The shorter variant contains a 24 aa deletion between residues 86 and 109. The amino acid sequence of the extracellular domain of mouse CD164 is 79% and 58% identical to that of the rat and human protein, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD164 Antibody (AF3118)(3)

Publications using AF3118

• L. Zhang, Y. Wang, H. Su Long non-coding RNA LINC00152/miR-613/CD164 axis regulates cell proliferation, apoptosis, migration and invasion in glioma via PI3K/AKT pathway Neoplasma 2020-01-01 [PMID: 32726126] (Western Blot, Human)
• L. Zhang, Y. Wang, H. Su Long non-coding RNA LINC00152/miR-613/CD164 axis regulates cell proliferation, apoptosis, migration and invasion in glioma via PI3K/AKT pathway Neoplasma 1/1/2020 [PMID: 32726126]
• Bae GU, Gaio U, Yang YJ, Lee HJ, Kang JS, Krauss RS Regulation of myoblast motility and fusion by the CXCR4-associated sialomucin, CD164. J. Biol. Chem., 2008-01-27;283(13):8301-9. 2008-01-27 [PMID: 18227060] (Western Blot, Mouse)

Bioinformatics

• Gene Symbol: CD164
• Uniprot:
  • Q9R0L9()