CD161 Antibody (14F2F11)


Western Blot: CD161 Antibody (14F2F11) [NBP2-14844] - Western blot analysis of a partial CD161 recombinant protein using CD161 antibody at 1 ug/ml.
Immunohistochemistry-Paraffin: CD161 Antibody (14F2F11) [NBP2-14844] - Analysis of CD161 in human kidney using CD161 antibody at 5 ug/ml.
Western Blot: CD161 Antibody (14F2F11) [NBP2-14844] - Analysis of a partial CD161 recombinant protein using CD161 antibody at 1 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB
0.5 mg/ml

CD161 Antibody (14F2F11) Summary

Amino acids 68-225 of human CD161 were used as the immunogen for this antibody.
IgG2b Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.05% BSA
0.05% Sodium Azide
0.5 mg/ml
Protein G purified

Reactivity Notes


Alternate Names for CD161 Antibody (14F2F11)

  • CD161 antigen
  • CD161
  • CLEC5B
  • CLEC5BC-type lectin domain family 5 member B
  • HNKR-P1a
  • killer cell lectin-like receptor subfamily B member 1
  • killer cell lectin-like receptor subfamily B, member 1
  • KLRB1
  • Ly59
  • Natural killer cell surface protein P1A
  • NKR
  • NKRP1
  • NKR-P1
  • NKRP1A
  • NKR-P1AMGC138614


CD161 is a C-Type Lectin Receptor, also known as NKR-P1A, previously found on NKT cells and subsets of T-cells. Phenotyping of cells that are functionally producing IL-17 has shown the one constant marker is CD161. While it had been shown previously that human CD4+ cells that produce both IL-17 and IFNg give rise to Th17/Th1 cells, indicating common etiology of these two T cell subsets, a clear marker for cells producing IL-17 is CD161. In fact, all cells characterized as the following subsets CD4+TCRab+, CD8+TCRab+, CD4-CD8-TCRab+, and CD4-CD8-TCRgd+ bearing CD161 also produce IL-17 but cells of these same phenotypes and functional marker which do not bear CD161 also do not produce IL-17. Induction of CD161 expression by transduction with RORC also induces IL-1R and IL-23R as well as the ability to produce IL-17. The ability to produce IL-17 and the induction of CD161 shows a strong dependency for RORC. Antibody to CD161 provides a probe for identifying IL-17 producing cells and offers a finer delineation of additional subsets derived from Th17 and their functional characteristics through cytokine mRNA expression or production.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP2-14844AF405
Alexa Fluor (R) 488 Labeled NBP2-14844AF488
Alexa Fluor (R) 647 Labeled NBP2-14844AF647
Alexa Fluor (R) 700 Labeled NBP2-14844AF700
Allophycocyanin Labeled NBP2-14844APC
Biotin Labeled NBP2-14844B
DyLight 350 Labeled NBP2-14844UV
DyLight 405 Labeled NBP2-14844V
DyLight 405LS Labeled NBP2-14844V3
DyLight 488 Labeled NBP2-14844G
DyLight 550 Labeled NBP2-14844R
DyLight 650 Labeled NBP2-14844C
DyLight 680 Labeled NBP2-14844FR
DyLight 755 Labeled NBP2-14844IR
HRP Labeled NBP2-14844H
PE Labeled NBP2-14844PE
PerCP Labeled NBP2-14844PCP

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Contact Information

Product PDFs


Gene Symbol KLRB1

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