CD11a/CD18 Antibody (hu1124 (Efalizumab)) - Azide and BSA Free

Immunohistochemistry: CD11a/CD18 Antibody (hu1124 (Efalizumab)) [NBP2-75912] - Anti-CD11a staining of formaldehyde fixed paraffin embedded rat spleen tissue, at 40x magnification. The human IgG1-chimeric version of hu1124 (NBP2-75912) was used to stain samples at a concentration of 3 ug/ml.

• Reactivity: Hu
• Applications: Flow, IHC, B/N
• Clone: hu1124 (Efalizumab)
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

CD11a/CD18 Antibody (hu1124 (Efalizumab)) - Azide and BSA Free Summary

• Description: Novus Biologicals Human CD11a/CD18 Antibody (hu1124 (Efalizumab)) - Azide and BSA Free (NBP2-75912) is a monoclonal antibody validated for use in IHC and Flow. Anti-CD11a/CD18 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
• Specificity: Binds to human LFA-1.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Human
• Gene: ITGAL
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Flow Cytometry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
• Buffer: PBS
• Preservative: 0.02% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CD11a/CD18 Antibody (hu1124 (Efalizumab)) - Azide and BSA Free

• biosimilar antibody
• biosimilars
• CD11 antigen-like family member A
• CD11a antigen
• CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
• integrin alpha-L
• integrin gene promoter
• integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
• Leukocyte adhesion glycoprotein LFA-1 alpha chain
• Leukocyte function-associated molecule 1 alpha chain
• LFA-1 alpha
• LFA-1
• LFA1A
• LFA-1A
• lymphocyte function-associated antigen 1

Background

The CD11/18 complex of glycoproteins are dimers comprised of a common beta chain and individual alpha chains (CD11a/18 or CD11b/18 and CD11c/18). CD11a/18 is a receptor for C3bi, a complement component, CD11b/18 is Lymphocyte Function Activator, and CDD11c/18 is a lectin-like glycoprotein thought to be important for mediation of cells to other surfaces.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD11a/CD18 Antibody (NBP2-75912)(1)

Publication using NBP2-75912

• Matsumoto K, Kurasawa T, Yoshimoto K et al. Identification of neutrophil beta 2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses Arthritis research & therapy 2021-05-06 [PMID: 33957974]

Bioinformatics

• Gene Symbol: ITGAL