CD109 Antibody (W7C5) - BSA Free

Flow (Cell Surface): CD109 Antibody (W7C5) [NBP2-75969] - Separation of human monocytes (red-filled) from CD109 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD109 (W7C5) purified antibody (concentration in sample 1 ug/ml) GAM APC.

Flow (Cell Surface): CD109 Antibody (W7C5) [NBP2-75969] - Staining pattern of human peripheral blood stained using anti-human CD109 (W7C5) purified antibody (concentration in sample 1 ug/ml) GAM APC.

• Reactivity: Hu
• Applications: Flow
• Clone: W7C5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CD109 Antibody (W7C5) - BSA Free Summary

• Additional Information: Clone W7C5 was used by HLDA to establish CD designation.
• Immunogen: WERI-RB-1 retinoblastoma cell line
• Specificity: The antibody MEM-174 recognizes CD11b antigen (Mac-1 alpha), a 165-170 kDa type I transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD109
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow (Cell Surface)
  • Flow Cytometry 1-4 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 15mM Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CD109 Antibody (W7C5) - BSA Free

• 150 kDa TGF-beta-1-binding protein
• activated T-cell marker CD109
• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
• CD109 antigen (Gov platelet alloantigens)
• CD109 antigen
• CD109 molecule
• CD109
• CPAMD7
• CPAMD7r150
• DKFZp762L1111
• FLJ38569
• FLJ41966
• Gov platelet alloantigens
• p180
• Platelet-specific Gov antigen
• RP11-525G3.1

Background

CD109 is a GPI-linked cell surface antigen expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T lymphoblasts, endothelial cells, and activated platelets (Lin et al., 2002 [PubMed 11861284]). In addition, the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune thrombocytopenia, and posttransfusion purpura, is carried by CD109 (Kelton et al., 1990 [PubMed 2346781]; Lin et al., 2002 [PubMed 11861284]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD109