CCRL2/CRAM-A/B Antibody (152211) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 152211
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

CCRL2/CRAM-A/B Antibody (152211) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human CCRL2/CRAM‑A/B. Stains human HCR-transfected cells but not irrelevant transfectants. It detects both the CRAM-A and CRAM-B isoforms.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCRL2/CRAM-A/B Antibody (152211) [Alexa Fluor™ Plus 680]

• ACKR5
• C-C chemokine receptor-like 2
• CCR11
• CCR6
• CCRL2
• CCRL2/CRAM-A/B
• chemokine (C-C motif) receptor-like 2
• Chemokine receptor CCR11
• Chemokine receptor X
• CKRX
• CKRXMGC116710
• CRAM
• CRAMA
• CRAM-A
• CRAMB
• CRAM-B
• FLJ55815
• HCR
• HCRMGC34104
• Putative MCP-1 chemokine receptor

Background

HCR, also known as CRAM-A, CRAM-B, CKRX and CCRL2, is a seven-transmembrane G-protein linked receptor that shares homology with other human chemokine receptors. Two isoforms were reported and designated CRAM-A and CRAM-B (1) that differ at their N-termini by the inclusion of an additional 12 amino acids on CRAM-A. HCR/CRAM is expressed at varying levels on a variety of peripheral blood cells including monocytes, neutrophils and T cells (2, 3).

1. Fan, P. et al. (1998) Biochem. Biophys. Res. Commun. 243:264.
2. Migeotte, I. et al. (2002) Eur. J. Immunol. 32:494.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.