CCR5 Antibody

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Immunohistochemistry: CCR5 Antibody [NB100-714] - Immunohistochemistry on paraffin section of human peripheral blood leukocytes

Product Details

Summary
Reactivity Hu, Pm, ViSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CCR5 Antibody Summary

Immunogen
Synthetic peptide 3YQVSSPIYDINYYTSEPCQKINVKQIAA30 corresponding to the N-terminal sequence of human CCR5
Localization
Plasma membrane
Specificity
This binds to CCR 5 receptors on human peripheral blood leukocytes as determined by immunohistochemistry.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCR5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA 1:25000
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
Publications
Read Publication using NB100-714.

Reactivity Notes

Macaque. Virus reactivity reported in scientific literature (PMID: 25067937).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
10mM KHPO4 and 0.14M NaCl, BSA @ 1mg/ml
Preservative
Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCR5 Antibody

  • C-C CKR-5
  • C-C motif chemokine receptor 5 A159A
  • CCCKR5
  • CC-CKR-5FLJ78003
  • CCR5
  • CCR-5
  • CD195 antigen
  • CD195
  • chemokine (C-C motif) receptor 5
  • chemokine receptor CCR5
  • chemr13
  • CKR5
  • CKR-5
  • HIV-1 fusion coreceptor
  • IDDM22CMKBR5C-C chemokine receptor type 5

Background

Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The chemokine receptor CCR 5 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of CCR 5 are important for HIV entry into the target cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ELISA, IHC, IHC-P

Publications for CCR5 Antibody (NB100-714)(1)

We have publications tested in 1 confirmed species: Virus.


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Bioinformatics

Gene Symbol CCR5
Entrez