Human, Macaque. Virus reactivity reported in scientific literature (PMID: 25067937)
Alternate Names for CCR5 Antibody
C-C motif chemokine receptor 5 A159A
chemokine (C-C motif) receptor 5
chemokine receptor CCR5
HIV-1 fusion coreceptor
IDDM22CMKBR5C-C chemokine receptor type 5
Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The chemokine receptor CCR 5 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of CCR 5 are important for HIV entry into the target cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.