CCR2 Antibody


Immunohistochemistry-Paraffin: CCR2 Antibody [NB100-701] - Paraffin section of mouse spleen.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, IHC, IHC-P
1.0 mg/ml

Order Details

CCR2 Antibody Summary

Synthetic peptide: SHSLFTRSIQELDEGATTPYDYDDGEPC, corresponding to N terminal amino acids 18-45 of the N-terminal domain of Mouse CCR2.
Cell Membrane
Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


  • Western Blot 1:500
  • Flow Cytometry 1:20
  • Immunohistochemistry 1:125
  • Immunohistochemistry-Paraffin 1:125
Application Notes
IHC-P: Antigen retrieval is not essential but may optimize staining. Optimal dilutions/concentrations should be determined by the end user. All dilutions given are minimums.

Reactivity Notes

Human reported in literature (PMID: 21719683).

Alternate Names for CCR2 Antibody

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor


CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Blogs on CCR2.

CCR2 or CD192
CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate...  Read full blog post.

CCR2: Affecting Autoimmunity via MCP1 interactions
CCR2, also known as CD192 (cluster of differentiation 192), is a chemokine receptor and is expressed by monocytes, activated T cells, B cells and natural killer cells. This protein is encoded by CCR2 gene in humans. CCR2 gene encodes two protein isofo...  Read full blog post.

MCP1: One Chemoattractant that's Hard to Resist
Monocyte Chemoattractant Protein (MCP1) is a potent monocyte attractant, is a member of the CC chemokine subfamily. MCP1 exerts its effects through binding to G-protein-coupled receptors on the surface of leukocytes targeted for activation and migrati...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CCR2

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