Human reported in literature (PMID: 21719683). Rat reactivity reported in scientific literature (PMID: 29359616).
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for CCR2 Antibody
C-C chemokine receptor type 2
chemokine (C-C motif) receptor 2
Monocyte chemoattractant protein 1 receptor
monocyte chemotactic protein 1 receptor
CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
CCR2 or CD192 CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate... Read full blog post.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Review this Product
Be the first to review our CCR2 Antibody and receive a gift card or discount.