CCL24/Eotaxin-2/MPIF-2 Antibody (RM0176-8M17) - Azide and BSA Free

• Reactivity: Hu, Mu
• Applications: WB, IHC, B/N
• Clone: RM0176-8M17
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

CCL24/Eotaxin-2/MPIF-2 Antibody (RM0176-8M17) - Azide and BSA Free Summary

• Immunogen: Mouse recombinant CCL24/Eotaxin-2/MPIF-2
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: CCL24
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:500-1:1000
• Application Notes: Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 24080254)

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24080254)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A or G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for CCL24/Eotaxin-2/MPIF-2 Antibody (RM0176-8M17) - Azide and BSA Free

• CCL24
• chemokine (C-C motif) ligand 24
• Ckb-6
• Eosinophil chemotactic protein 2
• Eotaxin-2
• member 24
• MPIF2
• MPIF-2
• MPIF2Myeloid progenitor inhibitory factor 2
• MPIF-2Small-inducible cytokine A24
• SCYA24CK-beta-6

Background

Eotaxin 2, also known as CCL24, is a part of a subfamily of the cytokine CC genes which are involved in immunoregulatory and inflammatory processes. Eotaxin 2 plays a role inducing chemotaxis in eosinophils when interacting with CCR3. This protein is known to have interactions with CCR3, CCR1, CCR10, CCR2 and CCR4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCL24/Eotaxin-2/MPIF-2 Antibody (NBP2-12109)(2)

Publications using NBP2-12109

• Jo WS, Kang S, Jeong SK et al. Low Dose Rate Radiation Regulates M2-like Macrophages in an Allergic Airway Inflammation Mouse Model Dose-response : a publication of International Hormesis Society 2022-08-18 [PMID: 36003321] (IHC-P, Mouse)
• Ciccia F, Alessandro R, Rizzo A et al. Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis. Rheumatology (Oxford) 2014-01-01 [PMID: 24080254] (IHC-P, Human)
  
  Details:
  rat anti-human CCL24 /Eotaxin 2 antibody used for IHC-P on paraffin-embedded sequential sections from patients with ankylosing spondylitis. Primary antibody used at 1:100 dilution, followed by goat anti-rat Cy5 secondary antibody (FIG. 4J and 4K).

Bioinformatics

• Gene Symbol: CCL24
• Uniprot:
  • Q9JKC0()