CCL23/Ck beta 8-1/MIP3 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

CCL23/Ck beta 8-1/MIP3 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human CCL23.
  
  

  Source: E. coli

  Amino Acid Sequence: NPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNS

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: CCL23
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-88079.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 24 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for CCL23/Ck beta 8-1/MIP3 Recombinant Protein Antigen

• C6 beta-chemokine
• CCL23/Ck beta 8-1
• chemokine (C-C motif) ligand 23
• Ck beta 8-1
• CKb8
• Ckb-8
• Ckb81
• CK-beta-8
• hmrp-2a
• Macrophage inflammatory protein 3
• MIP3
• MIP-3CK-BETA-8
• MPIF1
• MPIF-1Ckb-8-1
• Myeloid progenitor inhibitory factor 1
• SCYA23C-C motif chemokine 23
• small inducible cytokine subfamily A (Cys-Cys), member 23
• Small-inducible cytokine A23

Background

Macrophage Inflammatory Protein 3, also known as CCL23, is located on the p-arm of chromosome 9 with other CC cytokine genes which are involved in immunoregulatory and inflammatory processes. In patients with rheumatoid arthritis, high levels on CCL23(19-99) have been found in synovial fluids. This protein is known to have interaction with CCR1, CCR10, CCR2, CCR3 and CCR4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CCL23