CBX1 Antibody - BSA Free

Staining of human cell line U2OS shows localization to nucleoplasm & nuclear bodies.

Analysis in human cell line RT-4 and human cell line U-251 MG.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CBX1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit CBX1 Antibody - BSA Free (NBP3-24706) is a polyclonal antibody validated for use in WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody has been engineered to specifically recognize the recombinant protein CBX1 using the following amino acid sequence: ERLTWHSYPSEDDDKKDDKN
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CBX1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 µg/ml
  • Western Blot 0.04-0.4 µg/ml
• Application Notes: For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, 40% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CBX1 Antibody - BSA Free

• CBXM31HP1-BETA
• chromobox homolog 1 (Drosophila HP1 beta)
• chromobox homolog 1 (HP1 beta homolog Drosophila )
• chromobox homolog 1
• chromobox protein homolog 1
• Heterochromatin protein 1 homolog beta
• heterochromatin protein 1-beta
• heterochromatin protein p25 beta
• Heterochromatin protein p25
• HP1 beta homolog
• HP1 beta
• HP1Hsbeta
• HP1Hs-beta
• MOD1
• Modifier 1 protein
• p25beta

Background

HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CBX1