Cathepsin K Antibody

Western Blot: Cathepsin K Antibody [H00001513-D01P] - Analysis of CTSK expression in transfected 293T cell line by CTSK polyclonal antibody.Lane 1: CTSK transfected lysate(37.00 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Cathepsin K Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CTSK (NP_000387.1, 1 a.a. - 329 a.a.) full-length human protein. MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
• Specificity: CTSK - cathepsin K,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CTSK
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cathepsin K Antibody

• cathepsin K (pycnodysostosis)
• Cathepsin K
• Cathepsin O
• cathepsin O1
• Cathepsin O2
• Cathepsin X
• CTS02
• CTSK
• CTSO
• CTSO1
• CTSO2
• EC 3.4.22
• EC 3.4.22.38
• MGC23107
• PKND
• PYCD

Background

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTSK
• Entrez:
  • 1513(Human)
• Uniprot:
  • NP_000387.1(Human)