Cathepsin D Antibody

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Immunohistochemistry-Paraffin: Cathepsin D Antibody [NB120-826] - Staining of human prostate

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Cathepsin D Antibody Summary

Immunogen
Cathepsin D isolated from human liver
Localization
Cytoplasmic
Marker
Lysosomes Marker
Specificity
This antibody reacts with the zymogen as well as the activated form of cathepsin D. It stains fibroblasts and macrophages strongly but stains the myoepithelial cells of breast weakly. It also stains sweat ducts and glands in the skin, islets cells and granules of pancreatic acini.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CTSD
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
IHC: This antibody may be diluted to a titer of 1:75-1:200 in an ABC method. Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
Positive Control
Cathepsin D Lysate (NBL1-09590)

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS and BSA
Preservative
Sodium Azide
Purity
IgG purified

Alternate Names for Cathepsin D Antibody

  • cathepsin D (lysosomal aspartyl protease)
  • Cathepsin D
  • CPSD
  • CTSD
  • EC 3.4.23
  • EC 3.4.23.5
  • lysosomal aspartyl peptidase
  • lysosomal aspartyl protease
  • MGC2311
  • neuronal 10

Background

Cathepsin D has been reported to be involved in malignant tumour progression and with prognosis of various human cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CTSD
Entrez