CARD14 Antibody [Alexa Fluor® 750]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications ELISA, IHC, IHC-P
Alexa Fluor 750

CARD14 Antibody [Alexa Fluor® 750] Summary

CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2. Amino Acid Squence: DEQKKVVWTEQSPR
CARD14 antibody is human specific. At least three isoforms of CARD14 are known to exist; this antibody will only detect isoform 1. CARD14 antibody is predicted not to cross-react with other CARMA proteins.
Predicted Species
Mouse (92%). Backed by our 100% Guarantee.
Peptide affinity purified
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  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes


Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Peptide affinity purified


Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CARD14 Antibody [Alexa Fluor® 750]

  • bcl10-interacting maguk protein 2
  • BIMP2
  • CARD-containing MAGUK protein 2
  • card-maguk protein 2
  • Carma 2
  • CARMA2CARD-containing MAGUK 2 protein
  • caspase recruitment domain family, member 14
  • caspase recruitment domain-containing protein 14


The protein encoded by the CARD14 gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class ofproteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions ofthe plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying acharacteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure withCARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein knownto function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this proteinactivated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encodingdistinct isoforms have been reported. (provided by RefSeq)


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


Isotype Controls

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CARD14: The First Gene to be Linked to Psoriasis
Psoriasis is an autoimmune disease affects 3% of the United Kingdom's population and 7.5 million people in the United States are affected. This disease causes plaque formation on the skin due to an increased rate of skin cell growth. Psoriasis is trig...  Read full blog post.

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Gene Symbol CARD14