Carboxylesterase 1/CES1 Antibody

Western Blot: Carboxylesterase 1/CES1 Antibody [H00001066-D01P] - Analysis of CES1 expression in human placenta.

Western Blot: Carboxylesterase 1/CES1 Antibody [H00001066-D01P] - Analysis of CES1 expression in transfected 293T cell line by CES1 polyclonal antibody.Lane 1: CES1 transfected lysate(62.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Carboxylesterase 1/CES1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CES1 (AAH12418.1, 1 a.a. - 566 a.a.) full-length human protein. MWLPALVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL
• Specificity: CES1 - carboxylesterase 1 (monocyte/macrophage serine esterase 1),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CES1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Carboxylesterase 1/CES1 Antibody

• ACAT
• acyl coenzyme A:cholesterol acyltransferase
• Acyl-coenzyme A:cholesterol acyltransferase
• Brain carboxylesterase hBr1
• carboxylesterase 1 (monocyte/macrophage serine esterase 1)
• Carboxylesterase 1
• carboxylesterase 2 (liver)
• CEH
• CES1
• Ces-1
• CES1A2
• CES2EC 3.1.1.1
• cholesteryl ester hydrolase
• Cocaine carboxylesterase
• EC 3.1.1
• Egasyn
• HMSE1
• HMSECES1A1
• human monocyte/macrophage serine esterase 1
• liver carboxylesterase 1
• MGC117365
• Monocyte/macrophage serine esterase
• PCE-1
• REH
• Retinyl ester hydrolase
• Serine esterase 1
• SES1
• Ses-1
• SES1TGH
• TGH
• Triacylglycerol hydrolase

Background

Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CES1
• Entrez:
  • 1066(Human)
• Uniprot:
  • AAH12418.1(Human)