Carboxylesterase 1/CES1 Antibody [Alexa Fluor® 594]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 594

Carboxylesterase 1/CES1 Antibody [Alexa Fluor® 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Carboxylesterase 1/CES1
  His19-Leu565
  Accession # Q8VCC2
• Specificity: Detects mouse Carboxylesterase 1/CES1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse CES3 and recombinant human CES1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Carboxylesterase 1/CES1 Antibody [Alexa Fluor® 594]

• ACAT
• acyl coenzyme A:cholesterol acyltransferase
• Acyl-coenzyme A:cholesterol acyltransferase
• Brain carboxylesterase hBr1
• carboxylesterase 1 (monocyte/macrophage serine esterase 1)
• Carboxylesterase 1
• carboxylesterase 2 (liver)
• CEH
• CES1
• Ces-1
• CES1A2
• CES2EC 3.1.1.1
• cholesteryl ester hydrolase
• Cocaine carboxylesterase
• EC 3.1.1
• Egasyn
• HMSE1
• HMSECES1A1
• human monocyte/macrophage serine esterase 1
• liver carboxylesterase 1
• MGC117365
• Monocyte/macrophage serine esterase
• PCE-1
• REH
• Retinyl ester hydrolase
• Serine esterase 1
• SES1
• Ses-1
• SES1TGH
• TGH
• Triacylglycerol hydrolase

Background

Carboxylesterase 1/CES1 (also known as Ses-1 and Liver carboxylesterase 1) is a 60-63 kDa glycoprotein, member of a type-B carboxylesterase/lipase family localized to microsomal membrane and  lumen of endoplasmic reticulum. CES1 exists as a homotrimer and homohexamer and is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. CES1 is expressed mostly in liver, and with lower levels found in the lung. Over amino acids (aa) 19‑565, mouse CES1 shares 75% aa identity with human CES1.   

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.