Canine IL-2 DuoSet ELISA, 15 Plate

• Reactivity: Ca
• Applications: ELISA
• Conjugate: Biotin

Canine IL-2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Canine IL-2 DuoSet ELISA, 15 Plate

• Aldesleukin
• IL2
• IL-2
• IL-2lymphokine
• interleukin 2
• interleukin-2
• involved in regulation of T-cell clonal expansion
• Proleukin
• T cell growth factor
• T-cell growth factor
• TCGF

Background

IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.

Publications for IL-2 (DY1815)(3)

Publications using DY1815

• Zhao, J;Sun, Y;Sui, P;Pan, H;Shi, Y;Chen, J;Zhang, H;Wang, X;Tao, R;Liu, M;Sun, D;Zheng, J; DNA Vaccine Co-Expressing Hemagglutinin and IFN-? Provides Partial Protection to Ferrets against Lethal Challenge with Canine Distemper Virus Viruses 2023-09-04 [PMID: 37766279] (Ferret)
• N Maekawa, S Konnai, Y Asano, Y Sajiki, T Deguchi, T Okagawa, K Watari, H Takeuchi, S Takagi, K Hosoya, S Kim, H Ohta, Y Kato, Y Suzuki, S Murata, K Ohashi Exploration of serum biomarkers in dogs with malignant melanoma receiving anti-PD-L1 therapy and potential of COX-2 inhibition for combination therapy Oncogene, 2022-06-03;12(1):9265. 2022-06-03 [PMID: 35665759] (Canine)
• RM Gorczynski, T Maqbool, G Hoffmann Combined IMIG and Immune Ig Attenuate Allergic Responses in Beagle Dogs J Immunol Res, 2020-04-21;2020(0):2061609. 2020-04-21 [PMID: 32377529] (Canine)

FAQs for IL-2 (DY1815). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: IL2